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There was no knowledge thus far with the use of METROGEL-VAGINAL in pregnant patients. Metronidazole crosses the placental barrier and enters the fetal circulation rapidly. No fetotoxicity or teratogenicity was noticed when metronidazole was administered orally to Expecting mice at six moments the advised human dose (according to mg/m²); however, in one tiny analyze the place the drug was administered intraperitoneally, some intrauterine deaths have been noticed. The relationship of those conclusions towards the drug is mysterious.
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